Core contributor to both RespiriTB and RespiriNTM, focused on screening compounds against mycobacterial targets including mycothione reductase.
FFUND BV
Dutch SME providing high-throughput screening, structural biology, and organ-on-chip services for drug discovery in infectious disease and neuroscience.
Their core work
FFUND BV is a Dutch SME specializing in high-throughput screening, structural biology services, and microfluidic organ-on-chip technologies. They provide drug discovery support — particularly compound screening and target validation — for infectious disease and neuroscience research programs. Their work spans from identifying host-directed therapeutic targets for tuberculosis and non-tubercular mycobacteria to developing nervous-system-on-chip platforms for studying neurodegenerative diseases.
What they specialise in
Structural biology is a key keyword in both Respiri projects, suggesting FFUND provides structure-based drug design support.
Participant in CONNECT, developing nervous-system-on-chip technology using iPSCs, brain organoids, and neuroelectric interfaces.
Both RespiriTB and RespiriNTM aim to progress new molecular entities and first-in-human candidates for mycobacterial infections.
CONNECT project involves midbrain organoids, iPSC differentiation, and modeling of Parkinson's disease and other neurodegenerative conditions.
How they've shifted over time
All three of FFUND's H2020 projects began in 2019, so temporal evolution is limited. However, the keyword distribution reveals two distinct capability tracks: one centered on neuroscience and organ-on-chip engineering (CONNECT), and a larger emphasis on infectious disease drug discovery through screening and structural biology (both Respiri projects). The two Respiri projects extend to 2027, suggesting their drug discovery screening work is an expanding, longer-term commitment.
FFUND appears to be consolidating around high-throughput screening and structural biology services for anti-infective drug pipelines, making them a strong partner for translational infectious disease projects.
How they like to work
FFUND operates exclusively as a participant, never as coordinator, consistent with a specialist service provider role within larger research consortia. With 15 unique partners across 9 countries from just 3 projects, they work in medium-to-large international consortia and do not appear tied to a fixed set of collaborators. This suggests they are a flexible, plug-in partner valued for specific technical capabilities rather than project management.
FFUND has collaborated with 15 distinct partners across 9 countries through just 3 projects, indicating broad European reach relative to their size. Their network spans both health-focused drug discovery consortia and FET-funded neuroscience initiatives.
What sets them apart
FFUND combines high-throughput screening infrastructure with microfluidics and organ-on-chip expertise — an unusual dual capability for a small Dutch SME. This positions them to bridge the gap between traditional compound screening and advanced tissue-engineered disease models. For consortium builders, they offer plug-and-play screening and assay development services that can serve both infectious disease and neurodegeneration programs.
Highlights from their portfolio
- CONNECTFET-funded nervous-system-on-chip project combining iPSCs, brain organoids, and neuroelectric interfaces — a technically ambitious platform bridging neuroscience and bioengineering.
- RespiriNTMLargest funding share (EUR 234K) targeting non-tubercular mycobacteria with a first-in-human candidate goal, addressing a neglected but growing infectious disease area.
- RespiriTBCompanion project to RespiriNTM focused on tuberculosis, demonstrating FFUND's role as a consistent screening partner across related anti-infective pipelines.