All three projects (CHASSY, PAcMEN, MetaRNA) revolve around yeast as a production host and metabolic engineering of microbial cells.
EVOLVA AG
Swiss biotech SME engineering yeast cell factories to produce flavors, fragrances, oleochemicals and aromatic compounds by fermentation.
Their core work
Evolva is a Swiss biotech SME that engineers yeast strains to produce high-value ingredients — flavors, fragrances, oleochemicals and aromatic compounds — via fermentation instead of extraction from plants or petrochemistry. Their core capability is metabolic engineering: redesigning yeast cells as "cell factories" that convert sugars into target molecules at industrial scale. In H2020 they contributed this fermentation and strain-engineering expertise to academic consortia working on metabolic analysis, training, and next-generation chassis organism design.
What they specialise in
CHASSY explicitly targets versatile yeast chassis strains for production of oleochemicals and aromatic compounds.
PAcMEN (Predictive and Accelerated Metabolic Engineering Network) is an MSCA training network where Evolva hosts early-stage researchers.
MetaRNA applies RNA-based technologies to measure metabolites in individual cells — relevant to characterizing engineered strains.
How they've shifted over time
With only three projects running 2015–2021, Evolva's H2020 footprint shows a consistent rather than shifting focus: yeast-based metabolic engineering throughout. The later CHASSY project (2016–2021) sharpens this into a specific commercial angle — producing oleochemicals and aromatics in yeast — which aligns with Evolva's broader company pivot toward ingredient manufacturing. The trajectory points from generic metabolic engineering capability toward application-driven strain design for specific chemical product classes.
Moving from generic metabolic-engineering collaborations toward product-specific strain platforms (oleochemicals, aromatics) that reflect their commercial fermentation pipeline.
How they like to work
Evolva joins consortia as an industrial partner or third party, never as coordinator — bringing fermentation know-how to academic-led projects rather than running them. Across 3 projects they worked with 31 distinct partners in 11 countries, a hub-like rather than loyal network: each project brought a largely new set of collaborators. For partners, this means Evolva is reliable as a specialist industrial voice but will not carry coordination or reporting burden.
Worked with 31 unique partners across 11 countries in just three projects — a broad European academic network centered on metabolic engineering and synthetic biology labs, with Evolva as the industrial anchor.
What sets them apart
Evolva is one of the few European SMEs that actually operates commercial yeast fermentation for specialty ingredients, not just a research spin-out. Partnering with them gives a consortium direct access to industrial-scale strain engineering and scale-up reality checks that most university labs cannot provide. Their Swiss base also positions them as a neutral industrial partner in consortia that already include a large EU-based corporate lead.
Highlights from their portfolio
- CHASSYMost commercially relevant project — designs versatile yeast chassis strains specifically for producing oleochemicals and aromatics, directly matching Evolva's own product portfolio.
- PAcMENMSCA training network — Evolva hosts and trains early-stage researchers, giving them pipeline access to the next generation of metabolic engineers.
- MetaRNAUnusual cross-over into single-cell RNA-based metabolite measurement — a measurement capability that complements their strain-engineering work.