Central theme across Microflusa (coordinator), MUTAnTS, EVOdrops, PERTURBATIONS, AbioEvo, and earlier training networks.
ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS
Elite Paris research school specializing in microfluidics, soft matter physics, nanophotonics, and directed evolution at the physics-chemistry-biology interface.
Their core work
ESPCI Paris is an elite French graduate school specializing in physics, chemistry, and biology at their interfaces. Their core strength lies in microfluidics, soft matter physics, and colloidal materials — they design and fabricate advanced materials using droplet-based techniques, study fluid dynamics at micro and nano scales, and engineer proteins through directed evolution. They run a major interdisciplinary PhD programme (UPtoPARIS) training researchers across condensed matter, nanosciences, and biotechnology, and they are increasingly active in origin-of-life research and next-generation light-emitting nanomaterials.
What they specialise in
Spans from COLLDENSE and DoDyNet (polymer gels) through VITRIMAT (vitrimers), SHERO (self-healing robotics), and LubISS (slippery surfaces).
Phonsi focused on nanophotonics by nanocrystals, Ne2DeM (coordinator, EUR 1.5M) creates next-generation 2D light emitters, and colloidal synthesis runs through both.
EvoMachine-Phage, EVOdrops, and GuideArtifEvol all address enzyme or phage evolution using high-throughput microfluidic screening.
PHYMOT studies physics of microbial swimming and swarming; PERTURBATIONS probes gene regulatory networks in E. coli.
AbioEvo (coordinator, EUR 2M, 2021-2026) investigates conditions for evolution during abiogenesis using microfluidics — a new frontier for the group.
How they've shifted over time
In 2015–2018, ESPCI focused on fundamental condensed matter physics, photonics, hydrodynamics, and building microfluidic fabrication platforms (Microflusa, Phonsi, COLLDENSE). From 2019 onward, the emphasis shifted toward applied biology and life sciences — directed evolution, microbial motility, gene networks, and origin-of-life research — all powered by their established microfluidics infrastructure. A parallel thread emerged in smart functional materials: self-healing robotics (SHERO), vitrimers (VITRIMAT), and anti-contamination coatings (STELLAR).
ESPCI is pivoting its world-class microfluidics platform from materials fabrication toward biological and origin-of-life applications, making them a strong partner for bio-physics and synthetic biology consortia.
How they like to work
ESPCI balances leadership and partnership almost equally — they coordinated 14 projects and participated in 15, showing comfort in both roles. Their 155 unique partners across 31 countries indicate a wide, non-exclusive network typical of a research-intensive institution that attracts collaborators through scientific reputation. Heavy involvement in MSCA training networks (15 projects) signals they are well-practiced at hosting early-career researchers and managing multi-partner educational programmes.
ESPCI has built partnerships with 155 distinct organizations across 31 countries, giving them one of the broader collaboration networks among French higher education institutions in H2020. Their reach is pan-European with no strong geographic bias, reflecting the international prestige of a Paris-based grande école.
What sets them apart
ESPCI Paris occupies a rare niche: a small, highly focused grande école where physics, chemistry, and biology intersect under one roof. Unlike large universities that spread thin, ESPCI concentrates deep expertise in microfluidics, soft matter, and nanomaterials — areas where they both develop the fundamental science and build the experimental platforms. For consortium builders, this means a partner that brings both intellectual leadership and hands-on fabrication capability, especially at the interface between physical sciences and biology.
Highlights from their portfolio
- AbioEvoEUR 2M ERC-level grant (2021-2026) as coordinator, investigating the origin of life through microfluidics — a bold, high-visibility research direction.
- UPtoPARISLargest single grant (EUR 2.35M) funding ESPCI's interdisciplinary PhD programme, demonstrating institutional commitment to training across all their core disciplines.
- Ne2DeMEUR 1.5M coordinator project (2020-2026) on 2D light-emitting nanocrystals — bridges their colloidal synthesis and nanophotonics expertise into next-generation optoelectronics.