Both EU-ToxRisk and RISK-HUNT3R directly target NGRA frameworks, with RISK-HUNT3R explicitly focused on 'next generation testing strategies' and their regulatory acceptance.
COSMETICS EUROPE - THE PERSONAL CARE ASSOCIATION
European cosmetics industry association driving regulatory acceptance of next-generation, animal-free toxicology and risk assessment methods.
Their core work
Cosmetics Europe is the European trade association representing manufacturers and distributors of cosmetics and personal care products. In EU research, they act as the industry voice in large toxicology consortia, ensuring that next-generation safety testing methods are both scientifically credible and practically applicable to real formulation and ingredient challenges. Their core contribution is bridging academic research on mechanism-based toxicology with the regulatory and commercial realities of the personal care sector. They are particularly valuable for driving regulatory acceptance of new approach methodologies (NAMs) — a strategic priority for the entire industry given the EU's long-standing ban on animal testing in cosmetics.
What they specialise in
AOPs, systems toxicology, and molecular mechanisms are core keywords in EU-ToxRisk; quantitative AOP networks and toxicodynamics extend this work in RISK-HUNT3R.
RISK-HUNT3R introduces exposure modelling and toxicokinetics as newer capability layers built on top of the mechanistic toxicology foundation established in EU-ToxRisk.
As a trade association in both projects, Cosmetics Europe ensures research outputs address real formulation constraints and practical regulatory acceptance pathways for personal care products.
How they've shifted over time
In EU-ToxRisk (2016–2021), the focus was on building scientific infrastructure: AOPs, systems toxicology, cheminformatics, and mechanistic models for repeated dose and developmental toxicity. In RISK-HUNT3R (2021–2026), the emphasis shifted decisively toward applying and validating those methods — exposure modelling, toxicokinetics, real-world case studies, and regulatory acceptance. The trajectory is a deliberate move from scientific proof-of-concept to real-world implementation and uptake by regulators and industry practitioners.
They are moving from developing new toxicology tools to ensuring those tools are accepted by regulators and adopted across the industry, making them increasingly valuable for any consortium aiming to translate NAMs into approved safety workflows.
How they like to work
Cosmetics Europe consistently joins as a participant rather than leading projects, contributing industry expertise and end-user perspective to large academic-led consortia. With 58 unique partners across 14 countries from just 2 projects, they are embedded in very large flagship networks — not small, tight-knit collaborations. Their role is to represent a key industrial sector's needs, validate research outputs against real-world use cases, and open doors to regulatory acceptance.
Despite only 2 projects, Cosmetics Europe has built a network of 58 unique partners spanning 14 countries — reflecting the large-scale European flagship programs they participate in. Their network is European in reach, centered on toxicology research institutes, universities, and chemical industry players.
What sets them apart
As the authoritative voice of the European cosmetics industry in EU research, Cosmetics Europe brings something no academic or SME partner can replicate: direct access to industry testing needs, sector-wide regulatory intelligence, and the ability to mobilize industry-wide adoption of new methods. For any consortium working on alternative testing methods or chemical safety, having this association as a partner signals industry relevance and materially increases the likelihood of regulatory uptake. They also carry institutional continuity across multiple research generations — their involvement in both EU-ToxRisk and RISK-HUNT3R shows they are a sustained, strategic actor rather than an opportunistic participant.
Highlights from their portfolio
- EU-ToxRiskA major European flagship program on mechanism-based toxicity testing that laid the scientific foundation for animal-free safety assessment — Cosmetics Europe's involvement reflects the industry's strategic commitment to developing alternatives to animal testing at a formative stage.
- RISK-HUNT3RThe follow-on program (2021–2026) that takes NGRA from science to practice with an explicit focus on regulatory acceptance, representing the most advanced current effort to operationalize next-generation toxicology for real industry use.