Three projects (INMARE, BIOPEN, FuturEnzyme) focus on enzyme mining, biocatalysis, and AI-driven enzyme engineering for industrial products.
CLUSTER INDUSTRIELLE BIOTECHNOLOGIE EV
German industrial biotech cluster connecting enzyme technology, alternative proteins, and bioeconomy SMEs across Europe.
Their core work
CLIB is a German industrial biotechnology cluster association based in Düsseldorf that connects SMEs, researchers, and industry players in the bioeconomy space. They specialize in bridging the gap between biotechnology research and industrial application, particularly in enzyme technology, alternative proteins, and bio-based manufacturing. Their work spans from facilitating access to marine and environmental enzymes for industrial use to supporting insect-based protein production and SME capacity building across Europe. As a cluster organization, they act as a network orchestrator — organizing events, workshops, and connecting companies with venture capital and research consortia.
What they specialise in
FARMYNG targets industrial-scale mealworm production for fish-feed, pet-food, and protein extraction using automated robotic systems.
MPowerBIO focused on empowering SME clusters through business support, regional events, venture capital access, and replication guides.
INMARE explored metagenomic mining of marine extremophile enzymes for industrial and bioactive compound applications.
FuturEnzyme applies machine learning to enzyme discovery for greener detergents, bio-processed textiles, and cosmetic ingredients.
How they've shifted over time
CLIB's early H2020 work (2015–2019) centered on fundamental enzyme discovery from marine environments — metagenomic mining, biocatalysis, and genomics-based screening of extremophile organisms. From 2019 onward, their focus shifted decisively toward applied bioeconomy: insect-based protein production, AI-driven enzyme engineering for consumer products, and SME ecosystem building. This trajectory shows a clear move from upstream research participation toward downstream industrialization and business development support.
CLIB is moving from research-oriented enzyme projects toward industrialization, circular bioeconomy applications, and ecosystem building — expect them to seek partners with scale-up and manufacturing capabilities.
How they like to work
CLIB participates exclusively as a partner, never as coordinator — consistent with their role as a cluster association that contributes network access, dissemination, and industry linkages rather than leading technical research. With 71 unique consortium partners across 21 countries from just 5 projects, they operate in large, internationally diverse consortia. This makes them a strong "connector node" — useful for consortium builders who need a German bioeconomy network entry point and broad European reach.
Despite only 5 projects, CLIB has built connections with 71 distinct partners across 21 countries, reflecting their cluster role as a network multiplier. Their reach spans broadly across Europe with no narrow geographic concentration.
What sets them apart
CLIB sits at the intersection of industrial biotechnology research and business — a rare combination of deep enzyme technology knowledge and SME cluster management capability. Unlike pure research institutes, they understand commercialization pathways; unlike pure consultancies, they have genuine technical project experience in biocatalysis and bioprocessing. For consortium builders, they offer a ready-made network of German and European biotech SMEs plus the organizational infrastructure to run events, workshops, and capacity-building activities.
Highlights from their portfolio
- FuturEnzymeLargest funding (EUR 204,500), combines machine learning with enzyme engineering for circular economy products — represents CLIB's most advanced and current technical involvement.
- FARMYNGFlagship demonstration project for industrial-scale insect protein production, showing CLIB's reach beyond enzymes into alternative protein value chains.
- MPowerBIOPure cluster support project focused on helping bioeconomy SMEs cross the valley of death — reveals CLIB's core mission as an ecosystem builder.