SciTransfer
Organization

ASOCIATIA TRANSYLVANIAN INSTITUTE OF NEUROSCIENCE

Romanian neuroscience institute specializing in brain circuit imaging, optogenetics, and zebrafish-based screening for neurological diseases.

Research institutehealthRONo active H2020 projects
H2020 projects
3
As coordinator
2
Total EC funding
€1.0M
Unique partners
18
What they do

Their core work

The Transylvanian Institute of Neuroscience (TINS) is a Romanian research association focused on systems neuroscience, studying how neural circuits in the brain process sensory information and control behavior. They operate advanced imaging and electrophysiology labs, using techniques like 2-photon imaging and optogenetics to map brain activity. More recently, they have built zebrafish-based screening platforms for neurological diseases such as epilepsy and ALS, bridging basic neuroscience toward drug discovery and therapeutic target identification.

Core expertise

What they specialise in

Systems neuroscience and neural circuit mappingprimary
3 projects

All three projects (SyBil-AA, PhenoTECH, NEUROTWIN) involve understanding brain circuits, from alcohol addiction models to visual cortex dynamics.

Advanced neuroimaging (2-photon, fluorescence)primary
2 projects

NEUROTWIN lists 2-photon imaging as core capability; PhenoTECH builds large-scale fluorescent imaging platforms for zebrafish.

Zebrafish disease models and high-throughput screeningemerging
1 project

PhenoTECH (ERC Proof of Concept) developed motion detection and fluorescence imaging platforms for zebrafish models of ALS and epilepsy.

Optogenetics and electrophysiologysecondary
1 project

NEUROTWIN explicitly names optogenetics, electrophysiology, and behavior as core training and research areas.

Evolution & trajectory

How they've shifted over time

Early focus
Systems biology of addiction
Recent focus
Zebrafish disease screening platforms

TINS began as a participant in a large health consortium (SyBil-AA, 2016) studying systems biology of alcohol addiction — a computational and modeling-heavy effort. By 2020-2022, they shifted decisively toward applied neuroscience, building their own zebrafish screening platform for neurological disorders (PhenoTECH), and simultaneously investing in institutional capacity building through the NEUROTWIN twinning project. The trajectory shows a clear move from being a junior partner in addiction research to becoming a self-directed lab with translational ambitions in neurological disease screening.

TINS is transitioning from fundamental neuroscience toward translational drug screening using zebrafish models, positioning itself as a preclinical screening partner for neurological disorders.

Collaboration profile

How they like to work

Role: consortium_leaderReach: European10 countries collaborated

TINS predominantly leads its projects — coordinating 2 out of 3 H2020 grants, including a Widening Participation twinning project with 18 consortium partners across 10 countries. This is notable for a small Romanian research association and signals institutional ambition. Their one participant role was in a large multi-partner health consortium, suggesting they can operate both as consortium leaders in capacity-building contexts and as specialist contributors in larger research programs.

Despite only 3 projects, TINS has built a wide network of 18 unique partners across 10 countries, largely driven by the NEUROTWIN twinning project which was explicitly designed to connect them with established European neuroscience labs.

Why partner with them

What sets them apart

TINS is one of very few dedicated neuroscience research institutes in Romania, operating at a level that earned them an ERC Proof of Concept grant — a competitive marker of research quality. Their combination of fundamental brain circuit expertise with a purpose-built zebrafish phenotyping platform is unusual in the Widening countries, making them a strong partner for consortia needing Eastern European neuroscience capacity with genuine technical depth.

Notable projects

Highlights from their portfolio

  • PhenoTECH
    An ERC Proof of Concept grant — highly competitive and signals that their basic research has genuine translational potential for neurological disease screening.
  • NEUROTWIN
    Their largest project (EUR 668K) and a twinning grant designed to elevate TINS to the level of top European neuroscience institutes, indicating serious institutional growth ambitions.
Cross-sector capabilities
Drug discovery and preclinical screening (pharma)High-throughput biological assay development (biotech)Advanced imaging and optical instrumentation (photonics)
Analysis note: Profile based on only 3 projects, but the ERC Proof of Concept grant and twinning project provide meaningful signal about capabilities and trajectory. No website available for verification. The early-period keyword data was empty, so evolution analysis relies on project descriptions and dates rather than keyword comparison.