MicroCaT (2018-2021) is dedicated to Micro-tumor Guided Cancer Therapy Selection and was coordinated by 2CUREX with EUR 2.99M EC funding.
2CUREX A/S
Danish biotech SME testing cancer drugs on patient-derived micro-tumors to guide personalised therapy selection and overcome chemotherapy resistance.
Their core work
2CUREX is a Danish biotech SME developing functional precision medicine for cancer patients. Their core technology grows micro-tumors from patient biopsies and tests cancer drugs directly on these living mini-tumors to predict which therapy will actually work for that individual. This bridges a critical gap in oncology: instead of choosing chemotherapy based on genomics or guesswork, clinicians get functional evidence of drug response before treating the patient.
What they specialise in
Both MicroCaT and DECIDER target individualised cancer treatment decisions, with DECIDER explicitly addressing chemotherapy resistance.
DECIDER (2021-2026) integrates multiple data levels using data analysis, software engineering and artificial intelligence to improve treatment choices.
DECIDER is focused on overcoming chemotherapy resistance, a core oncology challenge where 2CUREX contributes functional testing capability.
MicroCaT was funded under the SME-2 scheme, indicating late-stage innovation and market preparation rather than basic research.
How they've shifted over time
In 2018-2021, 2CUREX ran as an SME-2 coordinator maturing its own micro-tumor platform toward market — a classic single-product commercialisation push. From 2021 onward they pivoted into the collaborative DECIDER consortium, where their wet-lab functional testing is combined with AI, software engineering and multi-omics data analysis. The trajectory is clear: from standalone device/assay development to embedding their platform inside data-driven, AI-enabled clinical decision systems.
They are moving from a standalone assay provider toward becoming the functional-data layer inside AI-powered oncology decision platforms — attractive for partners building integrated precision medicine offerings.
How they like to work
2CUREX is comfortable in both lead and partner positions: they coordinated their own SME-2 project and then joined a larger research consortium as a specialist contributor. With 15 unique partners across 7 countries in just two projects, their second project is clearly a broad European consortium rather than a small bilateral team. They behave like an SME that uses EU grants strategically — one project to push their own product, another to plug that product into a bigger scientific ecosystem.
Their network spans 15 partners across 7 countries, built almost entirely through the DECIDER consortium. The footprint is firmly European, anchored in Denmark with likely connections to Nordic and Northern European oncology research networks.
What sets them apart
Most precision oncology players sell genomic sequencing or algorithmic risk scores; 2CUREX sells functional evidence — the actual drug response of a patient's own tumor cells. That makes them a rare complement, not a competitor, to genomics-based and AI-based platforms. For a consortium or business partner, they are the group that can convert in-silico predictions into wet-lab confirmation on patient tissue.
Highlights from their portfolio
- MicroCaTTheir flagship project — coordinated by 2CUREX with EUR 2.99M under SME-2, dedicated entirely to commercialising their Micro-tumor Guided Cancer Therapy Selection technology.
- DECIDERA large European research consortium tackling chemotherapy resistance through AI and multi-level data integration, where 2CUREX contributes the functional testing layer.